Latent disease
Virus latency (or viral latency) is the ability of a pathogenic virus to lie dormant (latent) within a cell, denoted as the lysogenic part of the viral life cycle. A latent viral infection is a type of persistent viral infection which is distinguished from a chronic viral infection. Latency is the phase in certain viruses' life cycles in which, after initial infection, proliferation of virus particles ceases. However, the viral genome is not fully eradicated. The result of this is that the virus can reactivate and begin producing large amounts of viral progeny without the host being infected by new outside virus, denoted as the lytic part of the viral life cycle, and stays within the host indefinitely.
Virus latency is not to be confused with clinical latency during the incubation period when a virus is not dormant.

This is an excerpt from the article Latent disease from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
The article Latent disease at en.wikipedia.org was accessed 23 times in the last 30 days. (as of: 05/11/2014)
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What is the definition of Latent disease - Wiki Answers
What is a definition of a disease? Disease is a condition in which primarily an organ is not working harmonically with the others thus. What is the definitions of a ...
wiki.answers.com/Q/What_is_the_definition_of_Latent_disease
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Latent | Define Latent at Dictionary.com
adjective 1. present but not visible, apparent, or actualized; existing as potential: latent ability. 2. Pathology . (of an infectious agent or disease) remaining in ...
dictionary.reference.com/browse/latent
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Virus latency - Wikipedia, the free encyclopedia
Epigenotypes of Latent Herpesvirus Genomes. "DNA Methylation: Development, Genetic Disease and Cancer". Current topics in microbiology and immunology.
en.wikipedia.org/wiki/Virus_latency
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latent - definition of latent by the Free Online Dictionary, Thesaurus ...
(of an infectious agent or disease) remaining in an inactive or hidden phase; dormant. [1610–20; < Latin latent-, s. of latēns, present participle of latēre to lie ...
www.thefreedictionary.com/latent
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Latent Disease - Quest - World of Warcraft - Wowhead
Objectives. Kill Diseased Black Bears in Western Plaguelands, then loot 20 Plague Tangles that grow near their corpses. Plague Tangle ...
www.wowhead.com/quest=26934/
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Principles of Disease - Ohio State University at Mansfield
Inactive infection: A latent infection is inactive though continuing to infect, and which remains capable of producing symptoms.
www.mansfield.ohio-state.edu/~sabedon/biol2040.htm
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CDC | TB | Fact Sheets - Latent TB Infection vs. TB Disease
Sep 1, 2012 ... The Difference Between Latent TB Infection and TB Disease. What is TB? Tuberculosis (TB) is a disease caused by a germ called ...
www.cdc.gov/tb/publications/factsheets/general/ltbiandactivetb.htm
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Diagnosing Tuberculosis |TB Symptoms | TB Active & Latent Disease
Do I have TB?; patients with active and latent TB do not show any signs or symptoms; healthy people who contract tuberculosis may fight the infection through ...
www.oxfordimmunotec.com/Diagnosing_Tuberculosis_North_America
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Latent and potential coeliac disease.
Under the umbrella of coeliac disease (CD), or gluten-sensitive enteropathy, the concepts of silent, latent and potential CD have recently been introduced.
www.ncbi.nlm.nih.gov/pubmed/8783748
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Latent coeliac disease - National Center for Biotechnology Information
Do all children with coeliac disease need to stay on a gluten‐free diet for life? It's a question that has been asked ever since the connection between dietary ...
www.ncbi.nlm.nih.gov/pmc/articles/PMC2066082/
Search results for "Latent disease"
Google: approx. 11.900.000
Latent disease in science
[PDF]Management of Latent Tuberculosis Infection in Children and
Ana M.Alvarez, MD: University of ... Columbia University Medical Center. Pediatric .... tuberculosis disease and/or latent infection change as new knowledge and.
Mechanism for Control of HIV Latent Infection: Institute of Human ...
Mechanism for Control of HIV Latent Infection ... that HIV-1 has developed ways to achieve persistent infection that are different for each one of these reservoirs: ...
Annual incidence of latent tuberculosis infection among newly ...
Annual incidence of latent tuberculosis infection among newly employed nurses at a tertiary care university hospital. Lee K, Han MK, Choi HR, Choi CM, Oh YM, ...
Determining the Latent Tuberculosis Infection by IFN - γ Elispot ...
Jun 5, 2013 ... Determining the Latent Tuberculosis Infection by IFN - γ Elispot Assay in Healthcare Workers From University Hospitals of Shiraz, South West of ...
Identification and Management of Latent Tuberculosis Infection ...
May 15, 2009 ... Identification and Management of Latent Tuberculosis Infection. FERN R. HAUCK , MD, MS, University of Virginia School of Medicine, ...
Treatment of Latent Tuberculosis Infection in Children
May 19, 2013 ... Abstract. Treatment of latent tuberculosis infection (LTBI) is an effective way of ... Published by Oxford University Press on behalf of the Pediatric ...
Targeted Tuberculin Testing and Treatment of Latent Tuberculosis ...
Jun 9, 2000 ... ATS/CDC Statement Committee on Latent Tuberculosis Infection Membership List, June 2000 ... University of Wisconsin Medical School
DTBE - Questions and Answers - Introduction - Centers for Disease ...
Dec 21, 2012 ... People who have latent TB infection do not feel sick, do not have any ... But some people with latent TB infection go on to get TB disease.
[PDF]Latent Tuberculosis Infection(Positive PPD) and ... - Brown University
Latent Tuberculosis Infection(Positive PPD) and INH Treatment. PATIENT EDUCATION SERIES. BROWN UNIVERSITY HEALTH SERVICES ...
Migration and tuberculosis in the UK: targeting screening for latent ...
Jul 4, 2013 ... Strategies to detect latent TB infection (LTBI) in this population are, therefore, ... Diseases, Sophia Children's Hospital, Erasmus MC University ...
Books on the term Latent disease
Burton's Microbiology for the Health Sciences
Burton's Microbiology for the Health Sciences
Paul G. Engelkirk, Janet L. Duben-Engelkirk, Gwendolyn R. Wilson Burton, 2011
A Latent disease is a disease that is lying dormant, not currently manifesting itself. An infectious disease may go from being symptomatic to asymptomatic and then, some time later, go back to being symptomatic. Such diseases are referred to ...
Celiac Disease For Dummies
Celiac Disease For Dummies
Ian Blumer, MD, Sheila Crowe, 2010
Latent celiac disease (also sometimes called potential celiac disease) has three key features. The affected person: ✓ Does not have symptoms due to their celiac disease. ✓ Has typical blood test abnormalities of celiac disease (and, like the ...
Essential Readings in Infectious Disease Epidemiology
Essential Readings in Infectious Disease Epidemiology
Manya Magnus, 2012
In contrast, disease-intervention specialists acting conservatively should consider the same person to have an early latent infection and search for partners who may have been recently infected. Syphilis surveillance could consider such a ...
Bacterial Wilt Disease: Molecular and Ecological Aspects
Bacterial Wilt Disease: Molecular and Ecological Aspects
Philippe Prior, Caitilyn Allen, John G. Elphinstone, 1998
This includes the existence of latent infection and its undesirable effects. In recent years, breeding for groundnut resistance to bacterial wilt has progressed very slowly, with respect to enhancing the yield potential and resistance or tolerance to ...
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Blog posts on the term
Latent disease
Discovery of a Larger Than Expected Latent Reservoir of HIV Confounds Shock and Kill Cure Strategy
Just when some scientists were becoming more hopeful about finding a strategy to outwit HIV’s ability to resist, evade and otherwise survive efforts to rid it from the body, another hurdle has emerged to foil their plans, new research from Johns Hopkins shows.
www.infectioncontroltoday.com/news/2013/10/discovery-of-a-larger-than-expected-latent-reservoir-of-hiv-confounds-shock-and-kill-cure-strategy.aspx
Scientists identify molecular signals that rouse dormant HIV infection
Perhaps the single greatest barrier to curbing the spread of HIV/AIDS is the dormant, or 'latent,' reservoir of virus, which is out of reach of even the most potent medications. But now, scientists at the Gladstone Institutes have uncovered new clues that may help researchers awaken HIV from its slumber—laying ...
medicalxpress.com/news/2013-10-scientists-molecular-rouse-dormant-hiv.html
Investigation of Functional Activity of Cells in Granulomatous Inflammatory Lesions from Mice with Latent Tuberculous Infection in the New Ex Vivo Model
Clinical and Developmental Immunology is a peer-reviewed, open access journal that publishes original research articles, review articles, and clinical studies in all areas related to developmental immunology and clinical immunologic studies.
www.hindawi.com/journals/cdi/2013/371249/
Is this the answer to latent TB? | Science | theguardian.com
Only 10% of people with latent tuberculosis go on to develop the active disease. Monica Desai asks who stands to benefit if the latest research bears fruit
www.theguardian.com/science/blog/2010/aug/18/latent-tuberculosis-research
Vague Medical Monitoring Claim For Alleged “Lung Damage” Dismissed With Prejudice
By Isabella C. Lacayo Published on October 24, 2013 Print This Post.
product-liability.weil.com/class-action-law-suits/vague-medical-monitoring-claim-for-alleged-lung-damage-dismissed-with-prejudice/
Latent class analysis of reading, decoding, and writing performance us
Peer reviewed article authored by (Cogo-Moreira H, Carvalho CAF, Kida ASB, de Avila CRB, Salum GA, Moriyama TS, Gadelha A, Rohde LA, Moura LM, Jackowski AP, Mari JJ). Read article or submit your manuscript for publishing.
www.dovepress.com/latent-class-analysis-of-reading-decoding-and-writing-performance-usin-peer-reviewed-article-NDT
RNA signatures could be used for TB diagnostic test | Vaccine News Daily
Published on October 30, 2013 by Bryan Cohen.
vaccinenewsdaily.com/medical_countermeasures/328110-rna-signatures-could-be-used-for-tb-diagnostic-test/
"Host immunity and murine gammaherpesvirus 68 infection" by Pratyusha Mandal
Herpesviruses are large highly prevalent DNA viruses. They are some of the commonly occurring chronic infections of human beings. Herpesviruses infect hosts causing modest to inconsequential disease before establishing life-long latent infection in hosts. Although latent infection is largely restricted for expression of viral genes, herpesviruses often undergo reversion to lytic cycle with gene expression in a phase known as reactivation. High levels of herpesviruse reactivation and associated pathogenesis is observed in immunodeficient patients. In this body of work we have studied the infection of a gammaherpesvirus. Gammaherpesvirus latency and reactivation are primarily associated with several cancers in immunocompromised patients. Hence it is important to understand immune responses which control gammaherpesviruses reactivation and pathogenesis. Here we have used a murine gammaherpesvirus (murine gammaherpesvirus 68 or MHV68) to study roles of secreted glycoproteins called interferons in controlling infection. MHV68 is closely related to the human gammaherpesviruses which are hard to study owing to their species specificity. Usage of MHV68 helps us study a gammaherpesvirus interaction with vertebrate immune system in vivo. We identified that antiviral type I interferons (comprising of interferon alpha and beta) regulate MHV68 replication in vivo, in vitro and prevents latent virus from reactivation from peritoneal cells and splenocytes of mice by directly inhibiting MHV68 M2gene expression. Functional type I interferons induce signaling pathway which upregulate expression of several genes including transcription factors called interferon regulatory factors (IRF). We observed that type I interferon induced IRF2 directly binds a promoter region on M2gene which is a reactivation associated gene and represses M2 transcription and associated viral reactivation. A mutant virus which is unable to bind IRF2 in M2 promoter displayed increased replication, reactivation and M2 gene expression in vivo which results in increased host lethality in immunocompromised mice. Hence MHV68 cooperates with antiviral effects of the interferon system to facilitate maintenance of latency and minimize host lethality long term. ^ We further identified that although type I interferons significantly control MHV68 infection in vitro and in vivo, none of the effects are mediated by crucial interferon stimulated genes PKR and RNAseL. These interferon stimulated genes are considered to be among the first line of defense against any viral replication. Our investigations revealed that like the other human herpesviruses including the gammaherpesviruses, MHV68 also inhibits PKR-mediated antiviral response. Hence we have shown here a complicated relationship between a murine gammaherpesvirus and host type I interferon system. During replication,
docs.lib.purdue.edu/dissertations/AAI3592039/
Use of the WelTel mobile health intervention at a tuberculosis clinic in British Columbia: a pilot study | Journal of Mobile Technology in Medicine
Mia L. van der Kop MSc1,2, Jasmina Memetovic, MSc3, Kirsten Smillie, MA4, Jesse Coleman, MA5, Jan Hajek, MD3, Natasha Van Borek MA4, Darlene Taylor, MSc4,6, Kadria Alasaly, MD4, James Johnston, MSc, MD4, Richard T. Lester, MD3,4, Fawziah Marra, ...
www.journalmtm.com/2013/use-of-the-weltel-mobile-health-intervention-at-a-tuberculosis-clinic-in-british-columbia-a-pilot-study/
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