Phenadone
Methadone (also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon and many other names) is a synthetic opioid. It is used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependency. It was developed in Germany in 1937, mainly because Germany required a reliable internal source of opiates. Because it is an acyclic analog of morphine or heroin, methadone acts on the same opioid receptors as these drugs, and thus has many of the same effects. Methadone is also used in managing severe chronic pain, owing to its long duration of action, extremely powerful effects, and very low cost. Methadone was introduced into the United States in 1947 by Eli Lilly and Company. Abuse of methadone results in about 5,000 overdose deaths per year in the United States.
Methadone is mainly used in the treatment of opioid dependence. It has cross-tolerance (tolerance to similar drugs) with other opioids including heroin and morphine, and offers very similar effects, but a longer duration of effect. Oral doses of methadone can stabilise patients by mitigating opioid withdrawal syndrome or making it more tolerable. Higher doses of methadone can block the euphoric effects of heroin, morphine, and similar drugs. As a result, properly dosed methadone patients can reduce or stop altogether their use of these substances.
Methadone is approved for different indications in different countries. Common is approval as an analgesic and approval for the treatment of opioid dependence. It is not intended to reduce the use of non-opioid drugs such as methamphetamine, or alcohol.
A number of pharmaceutical companies produce and distribute methadone. The racemic hydrochloride is the only form available in most countries, such as the Netherlands, Belgium, France and in the United States, as of March 2008. The dextrorotary enantiomer of methadone, dextromethadone, is an NMDA antagonist rather than an opiate agonist. Therefore, methadone medications used for opiate addiction sometimes only contain levomethadone, the levorotary enantiomer. Levomethadone is available under the trade names Polamidone and Heptadon, among others.

This is an excerpt from the article Phenadone from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
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DrugBase: Drugs | Phenadone
Sep 6, 2010 ... Home > Drugs > Phenadone Details. Tradename. Phenadone. Generic Name. Category. Endocrine System. Form. Syrup. Composition.
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Phenadone - Pharmaceutical Drugs
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Phenadone - MeSH Result
1: Methadone A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to ...
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Flexyx: Phenadone (Generic name - Methadone) OnLine Information
Phenadone (Generic name - Methadone) OnLine Information - A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a ...
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Phenadone synonym by Babylon's thesaurus
Synonym of Phenadone: Wikipedia English - The Free Encyclopedia Methadone Methadone (also known as Symoron, Dolophine, Amidone, Methadose, ...
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phenadone 125ml | Fouda Pharmacy
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Phenadone in science
Methadone - Search - University of Massachusetts Medical School
"Methadone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged ...
Methadone | Profiles RNS - Search - Thomas Jefferson University
"Methadone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged ...
Methadone - Wikipedia, the free encyclopedia
Because it is an acyclic analog of morphine or heroin, methadone acts on the same ..... crashes than non-abuse patients in a study by Queensland University.
Methadone - University of Rochester Medical Center
"Methadone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged ...
Phonathon - Monmouth University
I didn't realize it when I started working here as a freshman, but being a caller at the Phonathon has given me all these skills and more. It's also pretty cool, ...
DrugBank: Methadone (DB00333)
Jun 13, 2005 ... Methadone is also used as part of the treatment of dependence on opioid drugs, although ..... Indiana University School of Medicine (2007).
[PDF]Chemical Summary: Methadone,(R)(-) (297-88-1) - ACToR
Phenadone. Physeptone. Polamivet. Racemic methadone. Sedo-Rapide. UNII- UC6VBE7V1Z. Component Name. Value. Teratogen. -> meets the University of ...
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Detailed Methadone dosage information for adults and children. Includes ... See additional information for Methadone. .... The Ohio State University Medical.
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Learn about the potential side effects of methadone. Includes ... Some side effects of methadone may not be reported. .... The Ohio State University Medical.
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Books on the term Phenadone
Greenknight
Greenknight
Allen Pedrick, 2001
We call it Phenadone—it works the same as cocaine. The new facility will have to be proven here in Tampa, then disassembled and smuggled to Cuba for full- scale operation. The new plant should be modeled after the pilot plant of Durant's  ...
GreenKnight
GreenKnight
Allen Pedrick, 2001
Allen Pedrick has worked for the Kennedy Space Center, NASA, in launch operations. He has traveled extensively in Europe, Africa, and the Middle East and holds BS and MS degrees. Other writing credentials include short stories, four novels, and various non-fiction articles. Mr. Pedrick is listed in Who's Who in the South and Southwest and belo...
Abstracts of Soviet Medicine: Basic medical sciences
Abstracts of Soviet Medicine: Basic medical sciences
1957
GUSEVA E. N. Sravnitelnoe deistvie promedola, fenadona i tekodina na dykhanie i eksperimentalnyi kashel Comparative effect of promedol, Phenadone and tecodin on respiration and experimental cough Farmakol. i Toksikol. 1956, 19/5 ...
Hazardous Chemicals Desk Reference
Hazardous Chemicals Desk Reference
Richard J. Lewis, Sr., 2008
... ENB500 PHENACETALDEHYDE DIMETHYL ACETAL see PDX000 P~ PHENACETIN see ABG750 PHENACHLOR see TIWOOO PHENACIDE see CDV100 PHENACYL CHLORIDE see CEA750 Phenadone see MDO750 PHENADOR-X ...
Routledge Diccionario Técnico Inglés
Routledge Diccionario Técnico Inglés
Routledge, 1997
Routledge. fenaceturico adj quimica phenaceturic fenacil m quimica phenacyl fenacilo m quimica phenacyl fenacina/ quimica phenazinc fenadona /quimica Phenadone fenantraquinona /quimica phenanthraquinone fenantrazina / qui mica ...
Index Nominum 2000: International Drug Directory
Index Nominum 2000: International Drug Directory
2000
OS: Methadone Hydrochloride В AN M IS: A 4624, Algolysine, Amidon, AN 148, Doloheptan, H.E.S., Hoechst 10820, Mecodin, Moheptan, Panalgen, Phenadone, Polamidon, Polamivet PH: Methadone Hydrochloride Ph. Eur. 3, USP 24 PH: ...
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