Plumbagin
Plumbagin or 5-hydroxy-2-methyl-1,4-naphthoquinone is an organic compound with the chemical formula C
11H
8O
3. It is regarded as a toxin and it is genotoxic and mutagenic.
Plumbagin is a yellow dye, formally derived from naphthoquinone.
It is named after the plant genus Plumbago, from which it was originally isolated. It is also commonly found in the carnivorous plant genera Drosera and Nepenthes. It is also a component of the black walnut drupe (Juglans nigra).

This is an excerpt from the article Plumbagin from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
The article Plumbagin at en.wikipedia.org was accessed 602 times in the last 30 days. (as of: 12/17/2013)
Images on Plumbagin
Preview image:
Original:
Search results from Google and Bing
1
1
1
Plumbagin - Wikipedia, the free encyclopedia
Plumbagin has been shown to induce cell cycle arrest and apoptosis in numerous cancer cell lines including melanoma, lung, breast and others. It triggers ...
en.wikipedia.org/wiki/Plumbagin
2
>30
2
Plumbagin Supplier | CAS 481-42-5 | Tocris Bioscience
View and buy high purity Plumbagin from Tocris Bioscience, the leading worldwide supplier of high performance life science reagents.
www.tocris.com/dispprod.php?ItemId=369082
3
>30
3
Plumbagin from Plumbago indica | Sigma-Aldrich
Sigma-Aldrich offers Sigma-P7262, Plumbagin from Plumbago indica for your research needs. Find product specific information including CAS, MSDS, protocols ...
www.sigmaaldrich.com/catalog/product/sigma/p7262?lang=en®ion=US
4
>30
4
Perspectives on medicinal properties of plumbagin ... - ResearchGate
Abstract: Plumbagin is one of the simplest plant secondary metabolite of three ... Moreover, Plumbagin effectively induces apoptosis and causes cell cycle arrest ...
www.researchgate.net/publication/232235977_Perspectives_on_medicinal_properties_of_plumbagin_and_its_analogs/file/9fcfd50aaf1c322044.pdf
5
>30
5
Plumbagin | C11H8O3 | ChemSpider
Structure, properties, spectra, suppliers and links for: Plumbagin.
www.chemspider.com/Chemical-Structure.9790.html
6
>30
6
plumbagin - PubChem
Structure, classification, information, physical and chemical properties for 5-Hydroxy-2-methyl-1,4-naphthoquinone, Plumbagine, 481-42-5, Plumbaein, ...
pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=10205
7
>30
7
Antimutagenic and antioxidant properties of plumbagin and other ...
May 17, 2013 ... The structure-function relationships of the naphthoquinone phytochemicals, Plumbagin, juglone, and menadione, have been studied with ...
www.ncbi.nlm.nih.gov/pubmed/23688616
8
>30
8
Plumbagin induces G2-M arrest and autophagy by inhibiting the ...
This study is the first to investigate the anticancer effect of Plumbagin in human breast cancer cells. Plumbagin exhibited cell proliferation inhibition by inducing ...
www.ncbi.nlm.nih.gov/pubmed/17172425
9
>30
9
Antimalarial activity of plumbagin in vitro and in ... - BioMed Central
Jan 12, 2014 ... Plumbagin is the major active constituent in several plants including Plumbago indica Linn. (root). This compound has been shown to exhibit a ...
www.biomedcentral.com/1472-6882/14/15
10
>30
10
Plumbagin - definition of Plumbagin by the Free Online Dictionary ...
n. 1. (Chem.) A crystalline substance said to be found in the root of a certain plant of the Leadwort (Plumbago) family. Want to thank TFD for its existence?
www.thefreedictionary.com/Plumbagin
Search results for "Plumbagin"
Google: approx. 73.100
Plumbagin in science
Suppressive Effects of Plumbagin on Invasion and Migration of ...
1Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University ...
Plumbagin induces apoptotic and autophagic cell death through ...
(4)Department of Pharmaceutical Science, College of Pharmacy, University of ... Plumbagin (PLB) has shown anti-cancer activity but the mechanism is unclear.
Plumbagin inhibits breast tumor bone metastasis and osteolysis by ...
Author information: East China Normal University and Shanghai ... In the present study, we examined the effects of Plumbagin on breast cancer bone metastasis.
Amelioration of Experimental Autoimmune Encephalomyelitis by ...
Oct 31, 2011 ... Plumbagin(PL), a herbal compound derived from roots of the medicinal ... Editor: Malú G. Tansey, Emory University, United States of America.
Plumbagin induces apoptotic and autophagic cell ... - Cancer Letters
Dec 16, 2013 ... Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer ...
Antimalarial activity of plumbagin in vitro and in ... - BioMed Central
Jan 12, 2014 ... Plumbagin is the major active constituent in several plants including ... International College of Medicine, Thammasat University (Rangsit ...
Plumbagin inhibits prostate cancer development in TRAMP mice via ...
Sep 13, 2012 ... ↵*Corresponding author Bilal Hafeez Contact email: hafeez{at}humonc.wisc.edu University of Wisconsin, Huuman Oncology, 1111 Highland ...
Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Induces ...
Dr. Chun-Ching Lin, Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung 807, ...
Acta Pharmacologica Sinica - Plumbagin attenuates cancer cell ...
Plumbagin attenuates cancer cell growth and osteoclast formation in the bone ... Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of ...
Acta Pharmacologica Sinica - Abstract of article: Plumbagin ...
Plumbagin attenuates cancer cell growth and osteoclast formation in the bone ... Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of ...
Books on the term Plumbagin
Chemistry of Organic Bodies, Vegetables
Chemistry of Organic Bodies, Vegetables
Thomas Thomson, 1838
SECTION X. — OF Plumbagin. This substance was discovered by M. Dulong d' Astafort, in the root of theplumbago Europaa, in 1828.* The bark of the root contains the most of it, and it may be extracted in the following manner : — Digest the ...
Microbial Inoculants for Improved yield of Plumbagin
Microbial Inoculants for Improved yield of Plumbagin
Danday Haribabu Rao, Tartte Vijaya and Duggina Pragathi, 2014
Danday Haribabu Rao is currently working as Botany Degree Lecturer in Sri Balasiva Yogendra Maharaj College,Kurnool.He has contributed many research and review articles in International and National Journals.
Medicinal Plants
Medicinal Plants
Alice Kurian, M. Asha Sankar, 2007
The trial also registered drastic reduction in Plumbagin content in stored roots. For samples stored under ambient conditions, Plumbagin content was negligible after 14 months, wherein, Plumbagin was converted to other compounds.
In vivo enhancement of Plumbagin in Plumbago zeylanica L.
In vivo enhancement of Plumbagin in Plumbago zeylanica L.
Namdeo B. Andhale and Avinash B. Ade, 2013
Namdeo B. Andhale is working as Lecturer of Botany in Juniour FC, Pune. He has 15 years teaching experience. Avinash B. Ade is working as Professor of Botany in the UoP, Pune. He has 15 years teaching and research experience.He has 50 publications in journals of repute and also co-authored 4 books. He has supervised 4 Ph.D. and 3 M.Phil. students.
Biotechnological Approaches for Sustainable Development
Biotechnological Approaches for Sustainable Development
M. Sudhakara Reddy, Sunil Khanna, 2004
RESULTS AND DISCUSSION Extraction, Purification and Characterization of Plumbagin Crude Plumbagin (0.67 % w/w of root powder) was obtained by ethanol solvent extraction. Partial characterization of Plumbagin was studied by using ...
German Cancer Therapies: Natural and Conventional Medicines That Offer Hope and Healing
German Cancer Therapies: Natural and Conventional Medicines That Offer Hope and Healing
Morton Walker, 2003
Written by an award-winning medical journalist, this is the first book to discuss the complementary therapies used by German doctors for the treatment of cancer. In clinics all across Germany, doctors have achieved a fully documented 88% remission rate in their cancer patients using natural, nontoxic treatments. This inspiring and informative book ...
Nutraceuticals and Cancer
Nutraceuticals and Cancer
Fazlul H. Sarkar, 2011
2008), Plumbagin was found to be the most effective inducer of apoptosis through its binding to and modulation of ER-alpha in BRCA1 silenced cells. In an earlier study, the effect of tamoxifen, emodin, and Plumbagin was analyzed in ...
Nutraceuticals and Cancer
Nutraceuticals and Cancer
Fazlul H. Sarkar, 2011
This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be medi...
Medicinal and Aromatic Plants XII
Medicinal and Aromatic Plants XII
Y. P. S. Bajaj, 2002
1990), chloroPlumbagin, droserone, and a bound form of Plumbagin - hydroPlumbagin 4-0-glucoside (Kreher et al. 1990). In the latter paper, it has also been proved that chloroPlumbagin is a natural, not arte- factual, product, and the structure ...
Medicinal and Aromatic Plants XII (Biotechnology in Agriculture and Forestry)
Medicinal and Aromatic Plants XII (Biotechnology in Agriculture and Forestry)
Toshiyuki Nagata and Yutaka Ebizuka, 2010
Medicinal and Aromatic Plants XII comprises 18 chapters. It deals with the distribution, importance, conventional propagation, micropropagation, tissue culture studies, and the in vitro production of important medicinal and pharmaceutical compounds in the following plants: Artemisia annua, Coriandrum sativum, Crataegus, Dionaea muscipula, Hyoscyamu...
Development of Google searches


Blog posts on the term
Plumbagin
physico-chemical standardisation and development of hptlc method ...
www.ijcpr.org/Issues/Vol3Issue1/261.pdf
Plumbagin - BML-AP505 - Enzo Life Sciences
Plumbagin - BML-AP505
www.enzolifesciences.com/BML-AP505/plumbagin/
Plumbagin from plumbago indica - Liste der Lieferanten - auch für 5-Hydroxy-2-methyl-[1 4]naphthoquinone, Plumbagin, Plumbagin from plumbago indica,
Erhalten Sie die Liste der Lieferanten und Anbieter für Plumbagin from plumbago indica and gleichen Chemikalien
www.buyersguidechem.com/chemikalien_lieferanten/Plumbagin_from_plumbago_indica
Investigation of Plumbagin Content in Plumbago indica Linn. Grown under Different Growing Systems
pharmacologia.co.uk/abstract.php?doi=pharmacologia.2012.57.60
Screening of Plumbago Species for the Bio-active Marker Plumbagin
informahealthcare.com/doi/pdf/10.1076/phbi.40.7.508.14685
Search Results
pubmedcentralcanada.ca/pmcc/solr/reg;jsessionid=2A5A26C16E2749D3603F6A6901DA04F9.eider?pageSize=25&term=&sortby=score+desc&filterAuthor=author%3A(%22Balachandran%2C+Indira%22)
Determination of Psoralen and plumbagin from its polyherbal oil formulations by an HPTLC densitometric method.(DIETARY SUPPLEMENTS)(high performance thin layer chromatography)(Report) | HighBeam Business: Arrive Prepared
Determination of Psoralen and Plumbagin from its polyherbal oil formulations by an HPTLC densitometric method.(DIETARY SUPPLEMENTS)(high performance thin layer chromatography)(Report) - Find Journal of AOAC International articles
business.highbeam.com/408580/article-1G1-201654254/determination-psoralen-and-plumbagin-its-polyherbal
Plumbagin Inhibits Osteoclastogenesis and Reduces Human Breast Cancer-induced Osteolytic Bone Metastasis in Mice through Suppression of RANKL Signaling
www.ncbi.nlm.nih.gov/pmc/articles/PMC3277663/
Development and validation of RP-HPLC method for simultaneous estimation of picroside I, plumbagin, and Z-guggulsterone in tablet formulation Akhade MS, Agrawal PA, Laddha K S - Indian J Pharm Sci
Scientific Publication of the Indian Pharmaceutical Association
www.ijpsonline.com/article.asp?issn=0250-474X;year=2013;volume=75;issue=4;spage=476;epage=482;aulast=Akhade
Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis. - ResearchGate
Publication » Identification of Plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis..
www.researchgate.net/publication/236615331_Identification_of_plumbagin_and_sanguinarine_as_effective_chemotherapeutic_agents_for_treatment_of_schistosomiasis
123