Quinolon
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. The original brand, Floxin, has been discontinued by the manufacturer in the United States on 18 June 2009, though generic equivalents continue to be available.
Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).
Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.
Like other quinolones, ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damange may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities. Ofloxacin has also been associated with severe psychiatric adverse reactions.

This is an excerpt from the article Quinolon from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
The article Quinolon at en.wikipedia.org was accessed 12 times in the last 30 days. (as of: 06/17/2014)
Images on Quinolon
Preview image:
Original:
Search results from Google and Bing
1
>30
1
Quinolone - Wikipedia, the free encyclopedia
The Quinolones are a family of synthetic broad-spectrum antibacterial drugs. The first generation of Quinolones began with the introduction of nalidixic acid in ...
en.wikipedia.org/wiki/Quinolone
2
>30
2
Structural Optimization of Quinolon-4(1H)-imines as Dual-Stage ...
Sep 10, 2013 ... Structural Optimization of Quinolon-4(1H)-imines as Dual-Stage Antimalarials: Toward Increased Potency and Metabolic Stability.
pubs.acs.org/doi/abs/10.1021/jm4011466
3
>30
3
Structural Optimization of Quinolon-4(1H)-imines as Dual-Stage ...
J Med Chem. 2013 Oct 10;56(19):7679-90. doi: 10.1021/jm4011466. Epub 2013 Sep 30. Structural Optimization of Quinolon-4(1H)-imines as Dual-Stage ...
www.ncbi.nlm.nih.gov/pubmed/24020770
4
>30
4
Flexyx: Quinolon (Generic name - Ofloxacin) OnLine Information
Quinolon (Generic name - Ofloxacin) OnLine Information - A synthetic fluoroQuinolone (fluoroQuinolones) antibacterial agent that inhibits the supercoiling activity ...
www.flexyx.com/Q/Quinolon.html
5
>30
5
Quino Martinez - Bulgaria | LinkedIn
View Quino Martinez's (Bulgaria) professional profile on LinkedIn. LinkedIn is the world's largest business network, helping professionals like Quino Martinez ...
bg.linkedin.com/pub/dir/Quino/Martinez
6
>30
6
Wilfredo Quino - Saudi Arabia | LinkedIn
View Wilfredo Quino's (Saudi Arabia) professional profile on LinkedIn. LinkedIn is the world's largest business network, helping professionals like Wilfredo Quino ...
sa.linkedin.com/pub/dir/Wilfredo/Quino
7
>30
7
Atardecer en Quino | Flickr - Photo Sharing!
Jan 6, 2012 ... Al suroeste de Victoria, con la bruma de los incendios, que gracias a la lluvia de ayer se apagaron en gran parte. Pink Floyd - Fat Old Sun Live ...
www.flickr.com/photos/monolive/6672372089/
8
>30
8
Flickr: Quino Molina
Flickr is almost certainly the best online photo management and sharing application in the world. Show off your favorite photos and videos to the world, securely ...
www.flickr.com/people/47716115@N03/
9
>30
9
Quino | Barnes & Noble
Barnes & Noble - Quino - Save with New Lower Prices on Millions of Books. FREE Shipping on $25 orders!
www.barnesandnoble.com/c/quino
10
>30
10
quino- - definition of quino- in the Medical dictionary - by the Free ...
Root of quinoline and quinone, hence used in many names of substances containing these structures (for example, quinine, quinol). Want to thank TFD for its ...
medical-dictionary.thefreedictionary.com/quino-
Search results for "Quinolon"
Google: approx. 1.120.000
Quinolon in science
Regulation of Pseudomonas Quinolone Signal Synthesis in ...
Regulation of Pseudomonas Quinolone Signal Synthesis in Pseudomonas ... of Microbiology and Immunology, East Carolina University School of Medicine, ...
Antibiotic medications - quinolones | University of Maryland Medical ...
May 31, 2013 ... Antibiotic medications - Quinolones. Selected Medications. Ciprofloxacin. Ciloxan Ophthalmic; Cipro. Levofloxacin. Levaquin; QUIXIN ...
The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ ...
... Centre for Biomolecular Sciences, University Park, University of Nottingham, ... Pseudomonas aeruginosa produces 2-heptyl-3-hydroxy-4(1H)-Quinolone ...
Plasmid-mediated quinolone resistance in clinical isolates of ...
Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, ... Although Quinolone resistance usually results from chromosomal mutations, ...
Quinolone - Wikipedia, the free encyclopedia
Essential structure of all Quinolone antibiotics: the blue drawn remainder of R ...... School of Pharmacy, University of Colorado Health Sciences Center, Denver, ...
Quinolone-3-Diarylethers: A New Class of Antimalarial Drug
Mar 20, 2013 ... Quinolone-3-Diarylethers: A New Class of Antimalarial Drug ... The 4(1H)-Quinolone-3-diarylethers are selective potent inhibitors of the ...
Fluoroquinolones Up Risk for Severe Dysglycemia in Diabetes
Aug 15, 2013 ... Use of fluoroQuinolones, in particular moxifloxacin, appears to ... say Hsu-Wen Chou, MS, from the National Taiwan University, Taipei, and ...
Development of the quinolones
Nalidixic acid, the first Quinolone to be developed, was obtained as an impurity during the manufacture of quinine. .... Oxford Journals Oxford University Press.
Cloning and Structure-Function Analyses of Quinolone- and ...
Oct 4, 2013 ... Results: QNS synthesizes Quinolone as the single product, whereas ACS .... Graduate School of Pharmaceutical Sciences, University of Tokyo, ...
New Classification and Update on the Quinolone Antibiotics ...
May 1, 2000 ... A new four-generation classification of the Quinolone drugs takes ... D., East Carolina University School of Medicine, Greenville, North Carolina.
Books on the term Quinolon
The Chemistry of Heterocyclic Compounds, Quinolines
The Chemistry of Heterocyclic Compounds, Quinolines
Gurnos Jones, 2009
... 153, 191 3,4-dialkyl 0r alkylaryl, 155 3,4-diaryl, 155 4(1H)-Quinolones, 2-aryl, 191 2(1H)-Quinolon-4-yl acetic acid, synthesis, 154 2(1H)-Quinolon-4-yl acetic acid, methyl ester, synthesis, 193 2(1H)-Quinolon-3-y1 acetic acid 6,7-dimethoxy,  ...
Quinolines
Quinolines
Gurnos Jones, 1977
0-Qumolon-4-yl acetic acid, methyl ester, synthesis, 193 2(l//)-Quinolon-3-yl acetic acid 6,7-dimethoxy, synthesis, 155 4-methyl, synthesis, 158 l-(2-Quinolyl) butadiene- 1 ,2,3 ,4-tetra- carboxylate, from quinoline, 34 5,6,7,8- Tetrachloroquinoline ...
Incorporating Science, Economics, and Sociology in ...
Incorporating Science, Economics, and Sociology in ...
Board on Agriculture and Natural Resources, Division on Earth and Life Studies, National Research Council, 2000
In Europe, the typical first-choice drug used to treat serious salmonellosis in humans is a Quinolon, ciprofloxacin. In cases when the salmonellosis has been caused by a Quinolon-resistant DT-104 strain, there is a risk of treatment failure, which ...
Victor Von Richter's Organic Chemistry: Carbocyclic and ...
Victor Von Richter's Organic Chemistry: Carbocyclic and ...
Victor von Richter, Richard Anschütz, Georg Schroeter, 1900
^44). n-Mitliyl Quinolon is also produced when ethoxyquinoline is healed with methyl iodide (li. 30, 930). I-Nitrocarbostyril, C9Hs(NOj)ON, melting at 1680, results from the action of alcoholic ammonia upon nitrocoumarin. 3 Oxycarbostyril  ...
Development of Google searches


Blog posts on the term
Quinolon
Ancaman Resistensi terhadap Quinolon | IDI Kabupaten Bekasi 2011-2014
Quinolon adalah salah satu golongan antibiotik yang cukup menjadi primadona dan pilihan pengobatan bagi para klinisi. Kekuatan obat ini sangat baik terutama untuk pasien-pasien dengan keluhan batuk. Dengan posologi 500mg single dose maupun pemberian 2 kali sehari, perbaikan pasien umumnya terlihat dalam 3-5 hari pengobatan. Tapi hanya sedikit yang menyadari bahwa Quinolon merupakan obat yang…
humasidikabbekasi.wordpress.com/2013/10/23/ancaman-resistensi-terhadap-quinolon/
Có thai dùng kháng sinh thuộc nhóm quinolon, hại gì? | Thực phẩm chức năng Vision, Sản phẩm Vision chính hãng - Happy Life Club
Có thai 3-5 tuần mà trước đó có điều trị viêm thận và dùng thuốc getzlox... có hại như thế nào.
thucphamthuocvision.com/co-thai-dung-khang-sinh-thuoc-nhom-quinolon-hai-gi/
Young Pharmacist: Antibiotika Golongan Quinolon
Antibiotik golongan Quinolon merupakan obat antibiotik yang dapat menjadi sesuatu yang sangat berbahaya bagi ibu hamil karena penggunaan antibiotik ini dapat berpotensi menyebabkan kecacatan. Sebab antibiotik ini bekerja untuk menghambat pembentukan inti sel.
normaidahhaiman.blogspot.com/2013/06/antibiotika-golongan-quinolon.html
RhizaL Pharmacy: OBAT QUINOLON
Asam Nalidiksat adalah prototip antibiotika golongan Kuinolon lama yang dipasarkan sekitar tahun 1960. Walaupun obat ini mempunyai daya antibakteri yang baik terhadap kuman gram negatif, tetapi eliminasinya melalui urin berlangsung terlalu cepat sehingga sulit dicapai kadar pengobatan dalam darah.
rhyzalop.blogspot.com/2013/05/obat-quinolon.html
Thận trọng khi dùng kháng sinh quinolon | Bệnh Viêm Phổi
Tâm lý người sử dụng thuốc thường hướng tới những thuốc thế hệ mới, nhất là các thuốc kháng sinh (KS). Quinolon là những KS quan trọng có phổ tác dụng rộng trong điều trị nhiễm vi khuẩn hiếu khí gram âm và gram dương. Việc ra đời nhóm KS này đã đem lại hy…
benhviemphoi.wordpress.com/2012/09/11/than-trong-khi-dung-khang-sinh-quinolon/
How to just take Cipro. Ny rapport Findes på MarketResearch.com Dækker Medical center Quinolon Monitoring | Medicin Uden Recept
Cipro on the web (PRWEB) seven juli 2003 The Medical center Quinolon Monitoring Research (United states) 2003 fås nu på MarketResearch.com, er et
medicinudenrecept.com/how-to-just-take-cipro-ny-rapport-findes-pa-marketresearch-com-daekker-medical-center-quinolon-monitoring/
goen.Ng.: Quinolon
Kuinolon yg penting ialah analog sintetik asam nalidiksat yg difluorinasiAktif thd berbagai bakteri gram (+) & gram (-)Kuinolon menghentikan sintesis DNA bakteri dgn menghambat DNA girase, sehingga mencegah relaksasi DNA superkoil yg dibutuhkan u/ transkripsi & duplikasi normalKuinolon yg lebih tua (as. Nalidiksat,as.
gunawan-alfatih.blogspot.com/2008/11/quinolon.html
MyBB - Internal Error
yendinh2.edu.vn/diendanyd2/showthread.php?tid=94652
12