Tau-crystallins
In anatomy, a crystallin is a water-soluble structural protein found in the lens and the cornea of the eye accounting for the transparency of the structure. It has also been identified in other places such as the heart, and in aggressive breast cancer tumors. Since it has been shown that lens injury may promote nerve regeneration, crystallin has been an area of neural research. So far, it has been demonstrated that crystallin β b2 (crybb2) may be a neurite promoting factor.

This is an excerpt from the article Tau-crystallins from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
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Tau-crystallin/alpha-enolase: one gene encodes both an enzyme ...
tau-Crystallin has been a major component of the cellular lenses of species throughout vertebrate evolution, from lamprey to birds. Immunofluorescence analysis ...
www.ncbi.nlm.nih.gov/pubmed/2462567
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Crocodilian tau-crystallin: overexpression, purification, and ...
tau-Crystallin is a taxon-restricted crystallin found in eye lenses of reptiles and a few avian species but presumably absent in mammals. The level of tau-crystallin  ...
www.ncbi.nlm.nih.gov/pubmed/12071699
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Tau-crystallins - The Free Dictionary
Crys´tal`lin (~l?n). n. 1. (Physiol. Chem.) See Gobulin. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle,  ...
www.thefreedictionary.com/Tau-crystallins
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Crystallin - Wikipedia, the free encyclopedia
In addition to these crystallins there are other taxon-specific crystallins which are only found in the lens of some organisms; these include delta, epsilon, tau, and ...
en.wikipedia.org/wiki/Crystallin
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Expression of the duck alpha-enolase/tau-crystallin gene in ...
Abstract. In many vertebrates, metabolic enzymes have been directly recruited to an additional structural role as crystallins in the eye lens. In some species the ...
www.fasebj.org/content/7/5/464
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URMC Research Network - tau-Crystallins
"Tau-crystallins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are ...
www.urmc.rochester.edu/profiles/profile/120743
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Penn State Profiles | tau-Crystallins
A type of crystallin that has been found in the lens (LENS, CRYSTALLINE) of certain species of VERTEBRATES. They are inactivated form of ...
profiles.psu.edu/profiles/profile/107269
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tau-Crystallins (definition) - Reference.MD
Definition: A type of crystallin that has been found in the lens (LENS, CRYSTALLINE) of certain species of VERTEBRATES. They are inactivated form of ...
www.reference.md/files/D038/mD038225.html
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Tau-Crystallins Overview - Expertscape.com
A type of crystallin that has been found in the lens (LENS, CRYSTALLINE) of certain species of VERTEBRATES. They are inactivated form of ...
www.expertscape.com/go/tau-crystallins
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tau-Crystallins | UCSF Profiles
D08.811.520.241.300.500.500. D12.776.306.366.962. Concept/Terms. Tau-crystallins. Tau-crystallins; tau Crystallins; tau-Crystallin; tau Crystallin; Crystallins, ...
profiles.ucsf.edu/profile/363946
Search results for "Tau-crystallins"
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Tau-crystallins in science
tau-Crystallins - University of Rochester Medical Center
"Tau-crystallins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are ...
Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define ...
Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define the principal ... Department of Pathology, Manchester University Medical School, England.
Trinucleotide repeat polymorphism at the alpha-enolase/tau ...
Trinucleotide repeat polymorphism at the alpha-enolase/tau-crystallin locus ... Wildlife Management and Biology, Texas Tech University, Lubbock 79409, USA.
The developmental expression of taxon-specific crystallins in the ...
Department of Molecular Biology, University of Nijmegen, The Netherlands. The three crystallins, alpha B-crystallin, tau-crystallin/alpha-enolase and ...
Tau-crystallin/alpha-enolase: one gene encodes ... - ResearchGate
Immunofluorescence analysis of the embryonic turtle lens, using antiserum to lamprey tau-crystallin showed that the protein is expressed throughout ...
Amyloid Fibrils Composed of Hexameric Peptides Attenuate ...
Apr 3, 2013 ... The amyloid-forming proteins tau, αB crystallin, and amyloid P protein are all found in lesions of multiple sclerosis (MS). Our previous work ...
The Journal of Cell Biology - The Rockefeller University Press
The Rockefeller University Press · The Journal of Cell Biology · The Journal of Experimental Medicine · The Journal of General Physiology. Institution: Google ...
Tau-crystallin/alpha-enolase: one gene encodes both an enzyme ...
tau-Crystallin has been a major component of the cellular lenses of species throughout vertebrate evolution, from lamprey to birds. Immunofluorescence analysis ...
Books on the term Tau-crystallins
Neuronal Degeneration and Regeneration: From Basic ...
Neuronal Degeneration and Regeneration: From Basic ...
F.W. Van Leeuwen, A. Salehi, R.J. Giger, 1998
... protein Cell type and subcellular location Tau-associated inclusions Glial cytoplasmic inclusion Neurofibrillary tangle ... disease Lichen amyloidosus Tau, ozB crystallin Tau Tau, neurofilament protein Neurofilament protein, ocB crystallin, ...
The Structure of Evolutionary Theory
The Structure of Evolutionary Theory
Stephen Jay Gould, 2002
The theory of evolution is regarded as one of the greatest glimmerings of understanding humans have ever had. It is an idea of science, not of belief, and therefore undergoes constant scrutiny and testing by argumentative evolutionary biologists. But while Darwinists may disagree on a great many things, they all operate within a (thus far) successf...
Focus on Eye Research
Focus on Eye Research
O. R. Ioseliani, 2005
Tau-Crystallin from the turtle lens: purification and partial characterization. Exp Eye Res. 40, 741-9 Wistow, G.J., Mulders, J.W. and de Jong, W.W.(1987) The enzyme lactate dehydrogenase as a structural protein in avian and crocodilian ...
Neuropathology: A Volume in the Foundations in Diagnostic Pathology Series, Expert Consult - Online and Print,...
Neuropathology: A Volume in the Foundations in Diagnostic Pathology Series, Expert Consult - Online and Print,...
2011
Neuropathology, a title in the Foundations in Diagnostic Pathology series, provides all of the latest and most essential information on neoplastic and non-neoplastic conditions of the central and peripheral nervous systems in a high-yield, easy-to-use format. Renowned expert Richard A. Prayson, MD, along with a premier group of neuropathologists, p...
Eye Proteins—Advances in Research and Application: 2013 Edition
Eye Proteins—Advances in Research and Application: 2013 Edition
2013
Crystalline. Form. ll. of. 7-(Dimethoxy-Methyl). Camptothecin,. Its. Use. as. Intermediate. and. Products. Obtained. Therefrom. By a News ... Patent number 8269007 is assigned to Sigma-Tau Industrie Farmaceutiche Riunite SpA (Rome, IT).
Multiple System Atrophy
Multiple System Atrophy
2013
This textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPC...
Permuted Medical Subject Headings
Permuted Medical Subject Headings
1999
... Binding Protein-Like Proteins tataricum Fagopyrum tataricum see Buckwheat Tattooing Tattooing tau Crystallins, tau sec Tau-crystallins tau-Crystallin see Tau-crystallins Tau-crystallins tau Proteins Tauopathies Tauopathies Taurine Taurine  ...
Neuropathology: A Reference Text of CNS Pathology, 3e
Neuropathology: A Reference Text of CNS Pathology, 3e
2013
Solve your toughest neurodiagnostic challenges with Neuropathology, 3rd Edition - the most information-packed, extensively illustrated neuropathology reference available! An expert author team presents more than 3,000 high-quality images - nearly all in full color - to provide unmatched visual guidance on the microscopic and gross pathologic presen...
Herpetic Eye Diseases
Herpetic Eye Diseases
1987
In other vertebrate groups there are several additional crystallins representing apparently unrelated gene families. 6-crystallin is the most studied of these and is present in birds and some reptiles (8). Of similar size are the tau-crystallin of turtle  ...
Avian Biochemistry and Molecular Biology
Avian Biochemistry and Molecular Biology
Lewis Stevens, 2004
The biology of birds is diverse and frequently differs significantly from that of other vertebrates. Many birds migrate or fly at high altitudes, while egg-laying and feather production places high demands on nutrient uptake and storage. This book is the only comprehensive and up-to-date survey of avian biochemistry and molecular biology available....
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Blog posts on the term
Tau-crystallins
Guardian Amyloid? Aβ Hexamers Help Multiple Sclerosis Mouse Model - AlzForum Alzheimer Research News
The Alzheimer Research Forum, a dynamic online scientific knowledge base, reports on the latest Alzheimer's scientific research and develops databases of genes, scientific articles, animal models, antibodies, medications, grants, research jobs, and more.
www.alzforum.org/new/detail.asp?id=3465
Alzheimer's Research & Therapy | Authorisation | Potential synergy between tau aggregation inhibitors and tau chaperone modulators
alzres.com/content/5/5/41
"Role of astrocytes in the pathogenesis of tauopathies" by Deepa V Dabir
Filamentous tau inclusions in neurons, astrocytes and oligodendrocytes are the neuropathological hallmark of both sporadic and familial tauopathies. The identification of pathogenic tau mutations in familial tsuopathies, termed frontotemporal dementia with parkinsonism linked to chromosome-17, provide unequivocal support for the hypothesis that defects in the tau gene are sufficient alone to cause neurodegeneration. While the role of deposition of filamentous tau aggregates in neurons as well as neuron loss in the neurodegenerative process is largely accepted, the relative contribution of the glial pathology is mostly unknown. The purpose of the studies presented in this dissertation is to better understand the role of astrocytic tau pathology in neuronal dysfunction and consequential development of neurodegeneration. First, we examined the role of heat shock proteins (HSPs) to disease pathogenesis of tauopathies with abundant glial pathology. We demonstrate increased expression of the small HSP, αB-crystallin specifically in glial tau inclusions of both sporadic and familial tauopathies suggesting a specific response by glia to the accumulation of misfolded protein. Secondly, to better understand the functional contribution of astrocytic tau pathology to disease pathogenesis, we developed the first transgenic mouse model of tau expression restricted to astrocytes. These Tg mice manifest an age-dependent accumulation of tau pathology in astrocytes similar to the human disease. We also demonstrate functional consequences of this pathology including reduced expression and activity of the filial glutamate transporters, GLT-1 and GLAST that correlated with compromised motor function. Thus, the GFAP/tau Tg mice suggest a role for altered astrocyte function in disease pathogenesis. Lastly, we generated mixed astrocyte/neuron cultures from the GFAP/tau Tg mice to assess the consequences of astrocytic tau expression on neuron survival. In mixed cultures generated from GFAP/tau Tg mice, we demonstrate reduced neuron survival that was blocked by NMDA receptor antagonists indicative of glutamate-mediated excitotoxicity. In conclusion, these studies propose that distinct mechanisms underlie the pathogenesis of glial versus neuronal tau pathology in tauopathies. It provides a better understanding of the significance of astrocytic tau pathology to the process of neurodegeneration. More importantly, they elucidate novel pathways that contribute to the disease pathogenesis of tauopathies. ^
repository.upenn.edu/dissertations/AAI3211054/
Lysosomes: Hotbeds Where Tau Oligomers Seed Aggregation? - AlzForum Alzheimer Research News
The Alzheimer Research Forum, a dynamic online scientific knowledge base, reports on the latest Alzheimer's scientific research and develops databases of genes, scientific articles, animal models, antibodies, medications, grants, research jobs, and more.
www.alzforum.org/new/detail.asp?id=2224
Spatiotemporal Characterization of Optic Nerve Degeneration after Chronic Hypoperfusion in the Rat
www.iovs.org/content/51/3/1483.full
Protein folding and misfolding: neurodegenerative diseases
The worldwide increasing age of populations brought the neurodegenerative diseases into the focus of interest. A number of the diverse human neurodegenerative diseases are now recognized as conformational diseases frequently caused ...
www.springer.com/biomed/book/978-1-4020-9433-0
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John Torday: Evolutionary Biology Redux
jtorday.blogspot.com/2013/11/evolutionary-biology-redux.html
SCUM2011 - Southern California Users of Magnets - Apr. 16 2011 - NMR Wiki
nmrwiki.org/wiki/index.php?title=SCUM2011_-_Southern_California_Users_of_Magnets_-_Apr._16_2011
recombinant peptides| What is recombinant peptides|Papers onrecombinant peptides |Research on recombinant peptides | Publications on recombinant pep
1. Biomed Mater.
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