Thioketal
In chemistry, a thioketal is the sulfur analogue of a ketal, with one of the oxygen replaced by sulfur. A dithioketal has both oxygens replaced by sulfur.
Thioketals can be obtained by reacting ketones or aldehydes with thioles.
Ketones can be reduced at neutral pH using the thioketal method. The thioketal prepared from the ketone can be easily reduced by catalytic hydrogenation using Raney nickel in a reaction known as the Mozingo reduction.

This is an excerpt from the article Thioketal from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
The article Thioketal at en.wikipedia.org was accessed 279 times in the last 30 days. (as of: 12/11/2013)
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Thioketal - Wikipedia, the free encyclopedia
In chemistry, a Thioketal is the sulfur analogue of a ketal, with one of the oxygen replaced by sulfur. A diThioketal has both oxygens replaced by sulfur. Thioketals ...
en.wikipedia.org/wiki/Thioketal
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Thioketal - OChemPal
Thioketal. A Thioketal is the sulfur analog of a ketal. eg. 1: eg. 2: eg. 3: see also cyclic Thioketal. Copyright © 2009 · All Rights Reserved. Admin Page · Log in.
science.uvu.edu/ochem/index.php/alphabetical/s-t/thioketal/
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Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA ...
Oct 10, 2010 ... Here, we present a delivery vehicle for siRNA, termed Thioketal nanoparticles ( TKNs), that can localize orally delivered siRNA to sites of ...
www.nature.com/nmat/journal/v9/n11/full/nmat2859.html
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thioketal (chemical compound) -- Encyclopedia Britannica
Thiols form sulfides and thioesters in reactions analogous to those of alcohols. They react readily with aldehydes and ketones to form thioacetals and Thioketals,  ...
www.britannica.com/EBchecked/topic/592239/thioketal
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Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA ...
Nat Mater. 2010 Nov;9(11):923-8. doi: 10.1038/nmat2859. Epub 2010 Oct 10. Orally delivered Thioketal nanoparticles loaded with TNF-α-siRNA target ...
www.ncbi.nlm.nih.gov/pubmed/20935658
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Orally delivered thioketal-nanoparticles loaded with TNFα-siRNA ...
Oct 10, 2010 ... Here, we present a delivery vehicle for siRNA, termed Thioketal nanoparticles ( TKNs), that can localize orally deliver siRNA to sites of intestinal ...
www.ncbi.nlm.nih.gov/pmc/articles/PMC3142359/
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Thioketal Nanoparticles: Researchers Develop Oral Delivery System ...
Oct 10, 2010 ... When delivered orally, Thioketal nanoparticles remain stable in non-inflamed tissues (top). However, at sites of intestinal inflammation the ...
www.gtresearchnews.gatech.edu/thioketal-nanoparticles/
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File:Thioketal Synthesis V.1.pdf - Wikimedia Commons
May 18, 2010 ... File:Thioketal Synthesis V.1.pdf. From Wikimedia Commons, the free media repository. Jump to: navigation, search. File; File history; File usage ...
commons.wikimedia.org/wiki/File:Thioketal_Synthesis_V.1.pdf
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thioketal - Wiktionary
Noun[edit]. Thioketal (plural Thioketals). (chemistry) The sulfur analogue of a ketal, with one of the oxygen atoms replaced by sulfur.
en.wiktionary.org/wiki/thioketal
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The thioketal product of a certain reaction is given below ... - Chegg
The Thioketal product of a certain reaction is given below. Draw the structure of: 0 pts ended This question is closed. No points were awarded. Anonymous.
www.chegg.com/homework-help/questions-and-answers/-q1631291
Search results for "Thioketal"
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Thioketal in science
Thioketal Nanoparticles: Researchers Develop Oral Delivery System ...
Oct 10, 2010 ... They encapsulated siRNA into engineered Thioketal nanoparticles and ... at the Georgia Institute of Technology and Emory University have ...
Orally delivered thioketal-nanoparticles loaded with TNFα-siRNA ...
Oct 10, 2010 ... 2Division of Digestive Diseases, Department of Medicine, Emory University, Atlanta, GA 30322. 3The Wallace H. Coulter Department of ...
Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA ...
Orally delivered Thioketal nanoparticles loaded with TNF-α-siRNA target ... Diseases, Department of Medicine, Emory University, Atlanta, Georgia, 30322, USA), ...
Mozingo reduction - Wikipedia, the free encyclopedia
The Mozingo reduction, also known as Mozingo reaction or Thioketal reduction, is a chemical reaction capable of fully reducing a ... Oxford University Press.
[PDF]Orally delivered thioketal nanoparticles loaded with ... - Murthy Lab
Oct 10, 2010 ... termed Thioketal nanoparticles (TKNs), that can localize orally ... Department of Medicine, Emory University, Atlanta, Georgia, 30322, USA, ...
[PDF]Transition metal promoted reactions: XIV. Novel reductive coupling ...
NOVEL REDUCTIVE COUPLING OF ThioketalS WITH ... Department of Chemistry, The Chinese University of Hong Kong, Shatin, N. T. (Hong Kong).
[PDF]Polystyryl-Mercury Trifluoroacetate. A Convenient and Mild Reagent ...
Convenient and Mild Reagent for Thioacetal and. Thioketal Hydrolysis'. Vaclav Janout2 and Steven L. Regen*. Department of Chemistry, Marquette University,.
Thioketal nanoparticles are formulated from a ROS-sensitive ...
Oct 10, 2010 ... From Orally delivered Thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines.
Inflammablog 5!: Thioketal Nanoparticles Targeting Inflammation
Oct 19, 2011 ... The article Orally delivered Thioketal nanoparticles loaded with .... by two courses at two schools: PSIO 495 at University of Arizona in Tucson, ...
DIANIONS OF GLYOXYLIC-ACID THIOKETALS - CONVENIENT ...
The University of British Columbia Vancouver campus. UBC Search ... Title, DIANIONS OF GLYOXYLIC-ACID ThioketalS - CONVENIENT ALPHA-KETO ACID ...
Books on the term Thioketal
Advanced Organic Chemistry: Part B: Reaction and Synthesis
Advanced Organic Chemistry: Part B: Reaction and Synthesis
Francis A. Carey, Richard J. Sundberg, 2007
... sodium borohydride in acetic acid can also be used as a reducing reagent in this reaction.281 Carbonyl groups can be converted to methylene groups by desulfurization of Thioketals. The cyclic Thioketal from ethanedithiol is commonly used.
Organic Chemistry II as a Second Language: Second Semester Topics
Organic Chemistry II as a Second Language: Second Semester Topics
David R. Klein, 2005
Building on the resounding success of the first volume (0-471-27235-3), Organic Chemistry as a Second Language, Volume 2 provides readers with clear, easy-to-understand explanations of fundamental principles. It explores the critical concepts while also examining why they are relevant. The core content is presented within the framework of predictin...
Advances in Nanotechnology Research and Application: 2011 ...
Advances in Nanotechnology Research and Application: 2011 ...
2012
Georgia Institute of Technology, Atlanta: Orally delivered Thioketal nanoparticles loaded with TNF-a-siRNA target inflammation and inhibit gene expression in the intestines Investigators publish new data in the report 'Orally delivered Thioketal ...
BIOS Instant Notes in Organic Chemistry
BIOS Instant Notes in Organic Chemistry
Graham Patrick, 2004
Instant Notes in Organic Chemistry, Second Edition, is the perfect text for undergraduates looking for a concise introduction to the subject, or a study guide to use before examinations. Each topic begins with a summary of essential facts−an ideal revision checklist−followed by a description of the subject that focuses on core information, with cle...
Organic Reactions And Their Mechanisms
Organic Reactions And Their Mechanisms
P S Kalsi, 2000
Synthesis of ketones (RCHO -» RRCO) The thioacetal can be alkylated once more to give a Thioketal. Thus one can introduce two alkyl groups sequentially into the 1 ,3-dithiane derivatives of formaldehyde. On hydrolysis the Thioketal gives the ...
Kaplan MCAT 2009-2010 Premier Program
Kaplan MCAT 2009-2010 Premier Program
Kaplan, Rochelle Rothstein, 2009
You can see that compound II is a cyclic Thioketal, so just as a diol was used to form a cyclic ketal, a dithiol would be needed to produce a cyclic Thioketal. Thus, choices (A) and (B) can be rejected right away. Choice (D) is also wrong, because ...
BIOS Instant Notes in Organic Chemistry
BIOS Instant Notes in Organic Chemistry
Graham Patrick, 2012
Thioketal. formation. Thioacetals and Thioketals are the sulfur equivalents of acetals and ketals and are also prepared under acid conditions (Figure 8). These can also be used to protect aldehydes and ketones, but the hydrolysis of these ...
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Blog posts on the term
Thioketal
Thioketale – Wikipedia
de.wikipedia.org/wiki/Thioketale
Inflammablog 5!: Thioketal Nanoparticles Targeting Inflammation
The article Orally delivered Thioketal nanoparticles loaded with TNF-alpha-siRNA target inflammation and inhibit gene expression in the intestines published in Nature Materials by Wilson, Dalmasso, Wang, Sitaraman, Merlin, and Murthy was one of the most dense articles we discussed this week, but arguably, one of the most well-thought out articles too in its processes. I'm going to do my best to summarize the logic that each experiment in the article was founded on.
inflammablog5.blogspot.com/2011/10/thioketal-nanoparticles-targeting.html
1,3-Dithiolanes, 1,3-Dithianes
www.organic-chemistry.org/protectivegroups/carbonyl/1,3-dithiolanes.htm
Ketone synthesis by hydrolysis or deprotection
www.organic-chemistry.org/synthesis/C2O/ketones/hydrolysisdeprotections.shtm
View PDF Version - RSC Publishing - Royal Society of Chemistry
pubs.rsc.org/en/content/articlepdf/2013/CS/C3CS35520A
Wake Forest : CHEM 123 : Practice Exam 2_CHEM 123
www.coursehero.com/file/7531731/Practice-Exam-2CHEM-123/
CAS # 150176-80-0, 4-(4-Chlorophenyl)-1-[3-[2-(4-Fluorophenyl)-1,3-Dithiolan-2-Yl]Propyl]Piperidin-4-Ol: more information.
chemBlink provides more information about CAS # 150176-80-0, 4-(4-Chlorophenyl)-1-[3-[2-(4-Fluorophenyl)-1,3-Dithiolan-2-Yl]Propyl]Piperidin-4-Ol
www.chemblink.com/moreProducts/more150176-80-0.htm
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