WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 is an enzyme that in humans is encoded by the WWP1 gene.
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.

This is an excerpt from the article WWP1 from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
The article WWP1 at en.wikipedia.org was accessed 114 times in the last 30 days. (as of: 09/03/2013)
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WWP1 - Wikipedia, the free encyclopedia
WWP1 has been shown to interact with KLF2, Reticulon 4 and CPSF6. ... a b " Entrez Gene: WWP1 WW domain containing E3 ubiquitin protein ligase 1".
en.wikipedia.org/wiki/WWP1
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NEDD4-like E3 ubiquitin-protein ligase WWP1 - Homo sapiens ...
Function. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin -conjugating enzyme in the form of a thioester and then directly transfers the ...
www.uniprot.org/uniprot/Q9H0M0
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wwp1.com - Wild West Productions ~ Freelance …
Our services range from residential and commercial moving, road crews and techicians for the entertainment industry, and we now also are involved in website design.
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WWP1 Gene - GeneCards | WWP1 Protein | WWP1 Antibody
Complete information for WWP1 gene (protein-coding), WW domain containing E3 ubiquitin protein ligase 1.
www.genecards.org/cgi-bin/carddisp.pl?gene=WWP1
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WWP1 WW domain containing E3 ubiquitin protein ligase 1 [Homo ...
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein ...
www.ncbi.nlm.nih.gov/gene/11059
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Wwp1 - Mouse Genome Informatics - The Jackson Laboratory
WWP1 WW domain containing E3 ubiquitin protein ligase 1 ...
www.informatics.jax.org/marker/MGI:1861728
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WWP1 (WW domain containing E3 ubiquitin protein ligase 1)
WWP1 (WW domain containing E3 ubiquitin protein ligase 1), Authors: Ceshi Chen. Published in: Atlas Genet Cytogenet Oncol Haematol.
atlasgeneticsoncology.org/Genes/WWP1ID42993ch8q21.html
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ENSG00000123124 - Ensembl
Gene: WWP1 ENSG00000123124 ... WWP1-003, ENST00000523863, 796, No protein product, -, Processed transcriptTranscripts that don't contain an open ...
www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000123124
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Anti-WWP1 antibody (ab43791) | Abcam
Rabbit polyclonal to WWP1 Primary antibodies datasheet (ab43791).
www.abcam.com/WWP1-antibody-ab43791.html
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Oncogene - Abstract of article: Ubiquitin E3 ligase WWP1 as an ...
Oncogenomics. Oncogene (2007) 26, 2386–2394. doi:10.1038/sj.onc.1210021; published online 2 October 2006 ...
www.nature.com/onc/journal/v26/n16/abs/1210021a.html
Search results for "WWP1"
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WWP1 in science
WWP1 Gene - GeneCards | WWP1 Protein | WWP1 Antibody
Complete information for WWP1 gene (protein-coding), WW domain ... OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, ...
Oncogene - Abstract of article: Ubiquitin E3 ligase WWP1 as an ...
Oct 2, 2006 ... Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate ... of Hematology and Oncology, Emory University School of Medicine, ...
E3 ubiquitin ligase, WWP1, interacts with AMPKα2 and down ...
Jan 4, 2013 ... Department of Anatomy, Korea University College of Medicine, Seoul, Korea. ... The yeast-two hybrid (YTH) approach identified WWP1, an E3 ...
WWP1 E3 Ligase Targets LATS1 for Ubiquitin-Mediated ...
We have provided in vitro and in vivo evidence that WWP1 is essential for LATS1 stability and ... Editor: Giuseppe Viglietto, University Magna Graecia, Italy ...
PLOS ONE: Ezrin Ubiquitylation by the E3 Ubiquitin Ligase, WWP1 ...
May 22, 2012 ... Current address: Sharjah institute for medical research, University of ... We show that ezrin binds to the WW domains of WWP1 via the ...
E3 ubiquitin ligase WWP1 - An intracellar target for aptameric ...
Feb 19, 2013 ... Conference Paper: E3 ubiquitin ligase WWP1 - An intracellar target for ... The University of Hong Kong, Hong Kong, 12-13 December 2012.
The E3 Ubiquitin Ligase WWP1 Selectively Targets HER4 and Its ...
WWP1 binds to all three Cyt1 PY motifs; the interaction with PY2 found ...... was done at Michael Hooker Microscopy Facility, University of North Carolina.
Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function ...
Ubiquitin E3 ligase WWP1 negatively regulates osteoblast function by inhibiting ... Department of Pathology and Laboratory Medicine, University of Rochester ...
TAZ antagonizes the WWP1-mediated KLF5 degradation and ...
Oct 31, 2011 ... TAZ inhibited WWP1-KLF5 protein interaction and WWP1-mediated KLF5 ubiquitination and ... Published by Oxford University Press. All rights ...
The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated ... - Bone
The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer ... Here, we studied the effects of WWP1 and itch, its closest family member, ...
Books on the term WWP1
Osteoimmunology: Interactions of the Immune and Skeletal Systems
Osteoimmunology: Interactions of the Immune and Skeletal Systems
Joseph Lorenzo, Yongwon Choi, Mark Horowitz, 2010
Among these WW domain proteins are the Src-responsive YAP protein, WWP1 which interacts with Schnurri3 to degrade Runx2, Smurf which functions 1 in response to TGFb and also targets Runx2 to the proteosome, the tumor suppressor ...
Wwp1
Wwp1
Lambert M Surhone, Mariam T Tennoe, Susan F Henssonow, 2011
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online.
Smad Signal Transduction: Smads in Proliferation, Differentiation ...
Smad Signal Transduction: Smads in Proliferation, Differentiation ...
Peter ten Dijke, Carl-Henrik. Heldin, 2006
These include WWP1/Tiul1, NEDD4-2, and Itch. Like Smurf2, WWP/Tiul1 interacts with all R-Smads and I-Smads, albeit with different affinity; however, strong binding of WWP1 and NEDD4-2 to Smad2 and Smad3 does not lead to ...
Modulation of protein stability in cancer therapy
Modulation of protein stability in cancer therapy
Kathleen Sakamoto, Eric Rubin, 2009
WWP1 WWP1 is a Nedd4-like E3 ubiquitin ligase that contains four tandem WW domains and a HECT domain. ... WWP1 also negatively regulates the TGFb tumor suppressor pathway by mediating the degradation Smad2, Smad4, and TGFb ...
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Blog posts on the term
WWP1
E3 Ubiquitin Ligase, WWP1, Interacts with AMPKα2 and Down-regulates Its Expression in Skeletal Muscle C2C12 Cells
www.jbc.org/content/288/7/4673
Wood Violins WWP1 Electric Violin Wah Pedal - electric violin amp
electricviolinamprecowwe.blogspot.com/2013/02/wood-violins-wwp1-electric-violin-wah.html
Expression of WWP1 and Its Correlation with ER, CerbB-2 and P53 in Breast Invasive Ductal Carcinoma Archive - Cancer Research Center
Breast cancer is one of the most common malignant tumors of female which endanger the health of women seriously. In recent years, the incidence increased obviously and has been in the forefront of malignant tumors of women. Breast cancer is a highly heterogeneous tumor, caused by a multi-factor and multi-step complex process. Breast cancer is the combined effects of the diseases by genetic and environmental factors. There are numerous gene mutations in breast cancer. It is a hot spot of clarific
www.rescancer.com/cervix-cancer/76474.html
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creative biomart - Recombinant Human WWP1, GST-tagged – Enzymes – Ceative Biomart
creativebiomart.edublogs.org/2010/09/27/recombinant-human-wwp1-gst-tagged-enzymes-ceative-biomart/
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