WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 is an enzyme that in humans is encoded by the WWP1 gene.
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.

This is an excerpt from the article WWP1 from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
The article WWP1 at en.wikipedia.org was accessed 114 times in the last 30 days. (as of: 09/03/2013)
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WWP1 - NEDD4-like E3 ubiquitin-protein ligase WWP1 - Homo ...
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to ...
www.uniprot.org/uniprot/Q9H0M0
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WWP1 Gene - GeneCards | WWP1 Protein | WWP1 Antibody
Complete information for WWP1 gene (protein-coding), WW domain containing E3 ubiquitin protein ligase 1, including: function, proteins, disorders, pathways, ...
www.genecards.org/cgi-bin/carddisp.pl?gene=WWP1
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WWP1 - Wikipedia, the free encyclopedia
NEDD4-like E3 ubiquitin-protein ligase WWP1 is an enzyme that in humans is encoded by the WWP1 gene. WW domain-containing proteins are found in all ...
en.wikipedia.org/wiki/WWP1
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WWP1 WW domain containing E3 ubiquitin protein ligase 1 [Homo ...
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein ...
www.ncbi.nlm.nih.gov/gene/11059
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OMIM Entry - * 602307 - WW DOMAIN-CONTAINING PROTEIN 1 ...
WWP1 belongs to the NEDD4 (602278) protein family. NEDD4 family proteins function as E3 ubiquitin ligases and are involved in protein trafficking, particularly  ...
www.omim.org/entry/602307
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WWP1 (WW domain containing E3 ubiquitin protein ligase 1)
The size of the WWP1 mRNA is about 4.2 Kb (Chen C, 2007). There are multiple splicing isoforms in the breast cancer cell line T47D (Flasza M, 2002). The open ...
atlasgeneticsoncology.org/Genes/WWP1ID42993ch8q21.html
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WWP1 E3 Ligase Targets LATS1 for Ubiquitin-Mediated ...
Apr 3, 2013 ... WWP1 (WW domain containing E3 ubiquitin protein ligase 1) is a member of the NEDD4-like family of HECT ubiquitin ligase and plays ...
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061027
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Wwp1 - Mouse Genome Informatics - The Jackson Laboratory
View mouse WWP1 Chr4:19608303-19708993 with: homology, phenotypes, function, expression, sequences, polymorphisms, proteins, references.
www.informatics.jax.org/marker/MGI:1861728
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Anti-WWP1 antibody (ab43791) | Abcam
Rabbit polyclonal antibody to WWP1. Published in 1 article,and validated in ICC/ IF, WB.
www.abcam.com/wwp1-antibody-ab43791.html
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WWP1 Symbol Report | HUGO Gene Nomenclature Committee
HGNC approved symbol report for the gene WWP1 (HGNC_ID:17004)
www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=17004
Search results for "WWP1"
Google: approx. 86.500
WWP1 in science
WWP1 E3 Ligase Targets LATS1 for Ubiquitin-Mediated ...
Apr 3, 2013 ... We have provided in vitro and in vivo evidence that WWP1 is essential for LATS1 ... Editor: Giuseppe Viglietto, University Magna Graecia, Italy.
Oncogene - Abstract of article: Ubiquitin E3 ligase WWP1 as an ...
Oct 2, 2006 ... Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate ... of Hematology and Oncology, Emory University School of Medicine, ...
[PDF]E3 Ubiquitin Ligase, WWP1, Interacts with AMPKα2 and ...
Jan 4, 2013 ... Department of Anatomy, Korea University College of Medicine, Seoul, Korea. * Running title: ... Results: AMPKα2 interacts with WWP1 and its.
E3 Ubiquitin Ligase, WWP1, Interacts with AMPKα2 and Down ...
Feb 15, 2013 ... Results: AMPKα2 interacts with WWP1, and its expression is .... Animal Care and Utilization Committee for Medical Science of Korea University.
WWP1 gene is a potential molecular target of human oral cancer ...
Publication » WWP1 gene is a potential molecular target of human oral cancer.. ... Department of Biological Science and Technology, China Medical University, ...
WWP1 Gene - GeneCards | WWP1 Protein | WWP1 Antibody
Complete information for WWP1 gene (protein-coding), WW domain ... OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, ...
Knockdown of WWP1 inhibits growth and induces apoptosis in ...
Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China.
Bortezomib prevents oncogenesis and bone metastasis of prostate ...
Jul 17, 2014 ... To explore activities of the ubiquitin ligase E3s WWP1, Smurf1 and Smurf2 .... been approved by Ethics Committee of Hebei Medical University.
Books on the term WWP1
Osteoimmunology: Interactions of the Immune and Skeletal Systems
Joseph Lorenzo, Mark Horowitz, Yongwon Choi, 2010
Among these WW domain proteins are the Src-responsive YAP protein, WWP1 which interacts with Schnurri3 to degrade Runx2, Smurf which functions 1 in response to TGFb and also targets Runx2 to the proteosome, the tumor suppressor ...
Enzymes—Advances in Research and Application: 2013 Edition
2013
(2013 Apr 05) Korea University, Se0ul: E3 Ubiquitin Ligase, WWP1, Interacts with AMPK alpha 2 and Down-regulates Its Expression in Skeletal Muscle C2C12 Cells By a News Reporter-Staff News Editor at Chemicals & Chemistry ...
Proteins—Advances in Research and Application: 2012 Edition
2012
antagonizes the WWP1-mediated KLF5 degradation and promotes breast cell proliferation and tumorigenesis “Kruppel-like factor 5 (KLF5) is a PY motif- containing transcription factor promoting breast cell proliferation. The KLF5 protein is ...
Smad Signal Transduction: Smads in Proliferation, ...
Peter ten Dijke, Carl-Henrik Heldin, 2007
WWP1/Tiul1 can also interact with the nuclear corepressor TGIF in response to TGF- stimulation, and interestingly, TGIF allows WWP1/Tiul1 to mediate the degradation of Smad2 (Seo et al., 2004). Noteworthy, the steady- state level of TGIF ...
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Blog posts on the term
WWP1
Anti-WWP1 antibody (ab43791) | Abcam
Rabbit polyclonal antibody to WWP1. Published in 1 article,and validated in ICC/IF, WB.
www.abcam.com/wwp1-antibody-ab43791.html
WWP1 | Viva
By viva-admin | Published June 14, 2013 | Full size is 181 × 174 pixels.
blog.viva.org/index.php/2013/06/14/going-deeper-wwp-update/wwp1/
WWP1 Antibody - Bethyl Laboratories, Antibody Manufacturer and Supplier
Rabbit anti-WWP1 Antibody, Affinity Purified AIP5, Tiul1, hSNEDD4-like E3 ubiquitin-protein ligase Atrophin-1-interacting protein 5, TGIF-interacting ubiquitin ligase 1, WW domain-containing protein 1, WW domain containing E3 ubiquitin protein ligase 1, atrophin-1 interacting protein 5, at
www.bethyl.com/product/A302-950A/WWP1_Antibody?referrer=WWP1
wwp1 - peperonity.com
peperonity.com/go/sites/mview/wwp1
PLOS ONE: WWP1 E3 Ligase Targets LATS1 for Ubiquitin-Mediated Degradation in Breast Cancer Cells
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061027
Abgent #AT4546a Monoclonal Mouse anti-WWP1 antibody - product details on 1DegreeBio - Independent Reviews on Life Science Products and Service Providers
Abgent #AT4546a Monoclonal Mouse anti-WWP1 antibody1DegreeBio - Unbiased reviews on Life Science products and service providers. Find product information, independent community reviews and rating, validation data, citation references, protocols and much more.
1degreebio.org/reagents/product/586468/?qid=0
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More cyclopaedia entries
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