Wolf–Kishner reduction
The Wolff–Kishner reduction is a chemical reaction that fully reduces a ketone (or aldehyde) to an alkane.[1][2]
The method originally involved heating the hydrazine with sodium ethoxide in a sealed vessel at about 180 °C. Other bases have been found equally effective. Diethylene glycol (DEG) is usually used as solvent.
Several reviews have been published.[3][4]

This is an excerpt from the article Wolf–Kishner reduction from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
The article Wolf–Kishner reduction at en.wikipedia.org was accessed 14 times in the last 30 days. (as of: 11/08/2013)
Images on Wolf–Kishner reduction
Preview image:
Original:
Search results from Google and Bing
1
1
1
Wolff–Kishner reduction - Wikipedia, the free encyclopedia
The Wolff–Kishner reduction is a reaction used in organic chemistry to convert carbonyl functionalities into methylene groups. In the context of complex molecule ...
en.wikipedia.org/wiki/Wolff%E2%80%93Kishner_reduction
16
2
2
Wolf-Kishner Reduction
Wolf-Kishner Reduction. Primary Reference. Kishner, N.J. Russ. Phys. Chem. Soc., 1911, 43, 582. Wolff, L. Ann., 1912, 394, 86. Todd, D. Org. React., 1948 ...
orgchem.chem.uconn.edu/namereact/wolffkishner.html
2
>30
3
Wolff-Kishner Reduction - Organic Chemistry Portal
Wolff-Kishner Reduction. The reduction of aldehydes and ketones to alkanes. Condensation of the carbonyl compound with hydrazine forms the hydrazone, and ...
www.organic-chemistry.org/namedreactions/wolff-kishner-reduction.shtm
3
>30
4
Wolff-Kishner Reduction - Chemwiki
Mar 4, 2014 ... These two steps can be combined into one reaction called the Wolff-Kishner Reduction which represents a general method for converting ...
chemwiki.ucdavis.edu/?title=Organic_Chemistry/Aldehydes_and_Ketones/Reactions_of_Aldehydes_%26_Ketones/Wolff-Kishner_Reduction
4
>30
5
Wolff-Kishner reduction is complementary to ... - OChemPal
The reaction of aldehydes and ketones with hydrazine in basic medium, which reduces the aldehyde or the ketone to a hydrocarbon, is called Wolff-Kishner ...
science.uvu.edu/ochem/index.php/alphabetical/w-x/wolff-kishner-reduction/
5
>30
6
Wolff-Kishner reduction ~ Name-Reaction.com
The Wolff-Kishner reduction is an organic reaction used to convert an aldehyde or ketone to an alkane using hydrazine, base, and thermal conditions.
www.name-reaction.com/wolff-kishner-reduction
6
>30
7
Wolff-Kishner Reduction: Carbonyl to Alkane is loaded - ChemTube3D
Wolff-Kishner Reduction: Carbonyl to Alkane. Background Colour: ... This then undergoes reduction by hot concentrated sodium hydroxide. The reaction works  ...
www.chemtube3d.com/red_wolff_kishner.html
7
>30
8
Wolff-Kishner Reduction - SynArchive
Mechanism, references and reaction samples of the Wolff-Kishner Reduction.
www.synarchive.com/named-reactions/Wolff-Kishner_Reduction
8
>30
9
Example of the Wolff-Kishner reduction procedure suitable for an ...
Example of the Wolff-Kishner reduction procedure suitable for an undergraduate organic lab experiment: Preparation of oxindole. PDF [517 KB].
pubs.acs.org/doi/abs/10.1021/ed070p332
9
>30
10
Wolff-Kishner Reduction - The WikiPremed MCAT Course
A page within the free MCAT Learning Program produced by Wisebridge Learning Systems. The topic under discussion here is Wolff-Kishner Reduction - The ...
www.wikipremed.com/mcat_course.php?code=0302080103000000
Search results for "Wolf–Kishner reduction"
Google: approx. 41.400
Wolf–Kishner reduction in science
Wolff-Kishner Reduction - Chemwiki
Mar 4, 2014 ... ... a Hydrazone to an Alkane; 3. Both Reactions Together Produces the Wolff-Kishner Reduction; 4. ... Steven Farmer (Sonoma State University).
[PDF]Reduction of Steroid Ketones and other Carbonyl Compounds by ...
UNIVERSITY]. Reduction of Steroid Ketones and other Carbonyl Compounds by Modified Wolff-. Kishner Method. BY HUANG-MINLON'. According to Dutcher ...
Wolff–Kishner reduction - Wikipedia, the free encyclopedia
The Wolff–Kishner reduction is a reaction used in organic chemistry to convert carbonyl functionalities into methylene groups. In the context of complex molecule ...
Wolff-Kishner Reduction - Organic Chemistry Portal
Wolff-Kishner Reduction. The reduction of aldehydes and ketones to alkanes. Condensation of the carbonyl compound with hydrazine forms the hydrazone, and ...
119 - Wolff-Kishner Reduction - University Publishing Online
It will be a good source of information for fundamental knowledge of organic synthesis to students at undergraduate level as well as industrial chemist.
Carbonyl Reactivity - Chemistry
In the LiAlH4 reduction, the resulting alkoxide salts are insoluble and need to be .... A possible mechanism for the Clemmensen reduction will be displayed by ...
Wolff-Kishner reduction is complementary to ... - OChemPal
Organic Chemistry Terminology for Undergraduate Chemistry Students. ... Wolff-Kishner reduction is complementary to Clemmensen reduction, which also ...
Wolff-Kishner Reduction: Carbonyl to Alkane is loaded - ChemTube3D
ChemTube3D contains interactive 3D animations for some of the most important organic reactions covered during an undergraduate chemistry degree.
Reductions - Department of Chemistry - University of Calgary
Reduction to Hydrocarbons (review of Chapter 12). reduction of carbonyl group to methylene. Clemmensen Reduction (acidic conditions). Zn(Hg) in HCl ...
[PDF]1,5-Hydride shift in Wolff-Kishner reduction of (20R ... - ScienceDirect
aDepartment of Organic Chemistry, University of Szeged, H-6720 Szeged Dóm ... suggests that the expected Wolff-Kishner reduction to a methylene group at the ...
Books on the term Wolf–Kishner reduction
Organic Chemistry
Organic Chemistry
David R. Klein, 2011
Students often say, “I studied 40 hours for this exam and I still didn’t do well. Where did I go wrong?” Most instructors hear this complaint every year. In many cases, it is true that the student invested countless hours, only to produce abysmal results. Often, inefficient study habits are to blame. The important question is: why do so many studen...
Comprehensive Organic Synthesis: Selectivity, Strategy, and ...
Barry M. Trost, Ian Fleming, 1991
The reaction is termed the Wolff-Kishner reduction in recognition of the two original independent discoverers.12 However, the initial recipes introduced proved tedious and unreliable with many structural, especially hindered, examples.
Organic Reactions Stereochemistry And Mechanism (Through ...
P S Kalsi, 2007
1 O Oxime Of e-caprolactam chiral oxime amide cyclohexanone (retention of configuration) 'Beckmann Baeyer - Villiger rearrangement oxidation Scheme 4.155 4.14 WOLFF-KISHNER AND CLEMMENSEN REDUCTIONS Both the methods ...
MCAT Prep Course
MCAT Prep Course
Garrett Biehle, 2013
Comprehensive, Rigorous Prep for the MCAT. At 1,340 pages, the MCAT Prep Course offers the most comprehensive and rigorous analysis of the MCAT available. Including, 1,059 practice problems! 103 MCAT-style passages, and detailed solutions to all problems The MCAT is one of few college entrance exams that actually tests some of the subjects you will...
Organic Reaction Mechanisms
Bansal, 1998
C»3 -HjO 5.4 The Wolff-Kishner Reduction 0^ ^CH3. 2K. This reaction also consists in the reduction of a carbonyl group of aldehydes and ketones to a methylene, analogous to the Clemmensen reduction, though under alkaline ...
Organic Chemistry Demystified 2/E
Organic Chemistry Demystified 2/E
2012
You don't need genius DNA to master organic chemistry! Whether you're taking a chemistry class or studying for the MCAT or DAT, Organic Chemistry Demystified is your formulas for learning or reviewing fundamental concepts and theories step-by-step. This practical guide eases you into this sometimes challenging subject, starting with atomi...
Synthetic Approaches in Organic Chemistry
Raj K. Bansal, 1996
NHJ ' X Since the discovery of the Birch reduction many improved methods for the Birch reduction have been developed for instance, use of other metals, amines instead of ammonia and addition of proton sources2. 2.2.4 The Wolff•Kishner ...
Development of Google searches


Blog posts on the term
Wolf–Kishner reduction
Wolff-Kishner Reduction
www.organic-chemistry.org/namedreactions/wolff-kishner-reduction.shtm
Wolff–Kishner reduction - Wikipedia, the free encyclopedia
en.wikipedia.org/wiki/Wolff%E2%80%93Kishner_reduction
Wolff-Kishner reduction ~ Name-Reaction.com
www.name-reaction.com/wolff-kishner-reduction
Wolff-Kishner Reduction | Chem-Station Int. Ed.
February 3, 2015 HOME Chemists Organic AnalyticalChem BioChem PhysicalChem SupraMolecularChem Interviews Molecules Papers OrganicChem Nanochem Inorganicchem Medchem ChemEngineering ChemicalBiology Material Reactions Blog Gallery SITEMAP.
www.chem-station.com/en/?p=1927
Wolff Kishner Reduction | Wolff Kishner Reduction Mechanism | Chemistry@TutorVista.com
Wolff-kishner Reduction is a Type of Organic Reaction in which the Ketones and Aldehydes are Reduced to Alkanes. Learn about Wolff Kishner Reduction Mechanism with the Help of our Free Online Tutors.
chemistry.tutorvista.com/organic-chemistry/wolff-kishner-reduction.html
On the mechanism of the Wolff-Kishner reduction
www.sciencedirect.com/science/article/pii/S0040403900915715
New Perspective to Chemistry: Wolff Kishner Reduction
Wolff-Kishner Reduction: This reaction is discovered by Ludwig Wolff and Nikolai Kischner in 1912. It is an organic reaction in which an aldehyde or ketone reduces to an alkane in the presence of hydrazine, base, and thermal condition. Example: Mechanism of the reaction: In general, the mechanism of the reaction involves following steps. In the starting, a hydrazone is formed by the condensation of hydrazine with the ketone or aldehyde substrate.  The obtained hydazone is deprotonated by alkoxide base. Proton transfer steps then result in the formation of a N=N bond. Deprotonation of nitrogen and a rearrangement reaction result in the formation of carbanion and the release of nitrogen gas.  The carbanion then picks up a proton from water to regenerate the base catalyst and provides the final alkane product..
shwetachandra.blogspot.com/2014/01/wolff-kishner-reduction.html
12