Xylazine is a drug that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. An analogue of clonidine, it is an agonist at the α2 class of adrenergic receptor. Xylazine has recently emerged as a recreational drug, especially in Puerto Rico.
As with other α2 agonists, adverse effects include bradycardia, conduction disturbances, and myocardial depression. Yohimbine (Yobine), tolazoline (commercial name Tolazine), and atipamezole (commercial name Antisedan) can be used to reverse xylazine effects. In veterinary anesthesia, xylazine is often used in combination with ketamine. No formal information in humans is available. Xylazine is sold by Bayer under the brand name Rompun.
Xylazine is also used to shorten the effects of musth on male elephants in Asia.

This is an excerpt from the article Xylazine from the Wikipedia free encyclopedia. A list of authors is available at Wikipedia.
The article Xylazine at en.wikipedia.org was accessed 5,938 times in the last 30 days. (as of: 06/09/2013)
Images on Xylazine
Preview image:
Search results from Google and Bing
The emerging of xylazine as a new drug of abuse and its health ...
The aim of this study was to document the use of "anestecia de caballo" (Xylazine ) and its consequences among drug users in Puerto Rico. The study combined ...
Xylazine HCL Injection Generic (Equine…
Free Shipping on most orders over $60. Great Low Price. Xylazine is a sedative and analgesic as well as a muscle relaxant. Xylazine HCl Injection is used in horses to ...
Xylazine - Wikipedia, the free encyclopedia
Xylazine is a drug that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.
Ketamine-Xylazine Combination for Rodent…
Ketamine-Xylazine Combination for Rodent Anesthesia. The combination of ketamine and Xylazine is popular for the anesthesia of many species including rodents.
Xylazine HCl Injection Veterinary Information from Drugs.com
May 17, 2013 ... All about Xylazine HCl Injection. View complete and up to date Xylazine HCl Injection veterinary information - part of the Drugs.com veterinary ...
Xylazine - FAO
Xylazine is a clonidine analoque. It acts on presynaptic and postsynaptic receptors of the central and peripheral nervous systems as an a 2-adrenergic agonist.
Xylazine Horse Tranquilizer: The Next Zombie Drug? | The Fix
Jan 8, 2013 ... Thanks to its proximity to the US, its numerous ports, and its unique political status, Puerto Rico is increasingly emerging as a center for drug ...
xylazine - anybody know anything? - Bluelight
http://en.wikipedia.org/wiki/Xylazine it says its an analgesic, sedative, and muscle relaxant. analgesic = painkiller, plus muscle relaxant...sounds ...
Guidelines for Xylazine - Animal Care & Use Program Duke U
Xylazine hydrochloride (Rompun) is a medication commonly used in laboratory animal anesthesia. It is an alpha2-agonist with sedative and analgesic ...
Xylazine - CCAC
Xylazine. Name: Xylazine. Trade Name(s): Rompun, Anased, Xylazine HCl Injection. Preparation: Sterile injectable liquid packaged in 20 ml vials with a ...
Search results for "Xylazine"
Google: approx. 615.000
Xylazine in science
Sheep & Goats - Texas Tech University
Xylazine (Rompun) Sheep .05-0.1 mg/kg IV ... Xylazine (Rompun) Goats ... © 2012 Texas Tech University | All Rights Reserved | Updated: 8/24/2012 07:51:36 ...
Injectable Anesthesia — Penn State University
Oct 25, 2011 ... Rat. Rabbit. Ketamine:Xylazine ... Ketamine:Xylazine: Acepromazine ... Xylazine is available in concentrations of 20 mg/ml and 100 mg/ml.
The ocular effects of xylazine in rabbits, cats, and monkeys.
Department of Pharmacology, Texas Tech University Health Sciences Center, Lubbock. Xylazine is an agent frequently used in combination with ketamine to ...
Xylazine | Medical Research and Treatment Information from Medify
Learn about Xylazine including its side effects, effectiveness, and alternatives ... On what conditions has Xylazine been studied? ... University of California-Davis ...
Xylazine - University of Nairobi Digital Repository
Browsing by Subject "Xylazine". University of Nairobi Digital Repository. Login · Repository Home; →; Browsing by Subject. JavaScript is disabled for your ...
Rat Formulary » Research Committees » Boston University
Higher ketamine dose with lower Xylazine dose are used for less invasive procedures ... In general, higher doses of Xylazine with concomitant lowering of the ...
Mouse Formulary » Research Committees » Boston University
Higher ketamine dose with lower Xylazine dose are used for less invasive procedures ... In general, higher doses of Xylazine with concomitant lowering of the ...
Georgetown University, Division of Comparative Medicine
May 22, 2013 ... Home | Georgetown University | GUACUC ... 1Cocktail: Mix 1.0 ml of Ketamine 100 mg/ml, 0.5 ml of Xylazine 20 mg/ml, and 8.5 ml sterile ...
"Xylazine and butorphanol: survey of field use in the horse" by ...
A field survey was made on the combined use of Xylazine and butorphanol for standing equine restraint (52 practitioner university clinics). A suggested initial ...
The effects of a loading dose followed by constant rate infusion of ...
Oct 11, 2012 ... The effects of a loading dose followed by constant rate infusion of Xylazine compared with romifidine on sedation, ataxia and response to ...
Books on the term Xylazine
The veterinary formulary
The veterinary formulary
Yolande M. Bishop, British Veterinary Association, 2005
1 ) in dogs and cats may be advantageous to reduce salivation and the bradycardic effects of Xylazine. ... Xylazine may initially cause bradycardia and second degree heart block, which resolve after approximately 10 minutes. Arterial blood ...
Clinical Pharmacology
Clinical Pharmacology
Cynthia R. L. Webster, 2001
Xylazine is an a2 adrenergic receptor agonist that results in dose-dependent sedation, analgesia, and muscle relaxation ... The peripheral effects of Xylazine are related to blockage of a adrenergic receptors on vascular smooth muscle, ...
Anesthesia and analgesia in laboratory animals
Anesthesia and analgesia in laboratory animals
Richard E. Fish, 2008
Ketamine has been combined with Xylazine (Dittmar et al., 2004; Schwenke and Cragg, 2004; Wixson et al., ... In male SpragueDawley rats, an IP injection of 40/5 mg/kg ketamine/Xylazine resulted in a 32.3% decrease in MAP (Wixson et al., ...
Saunders Handbook of Veterinary Drugs
Saunders Handbook of Veterinary Drugs
Mark G Papich, 2007
Xylazine. hydrochloride. zye'lah-zeen hye-droe-klor'ide Trade and Other Names: Rompun and generic brands Functional Classification: Alpha: adrenergic agonist . Analgesic, Sedative Pharmacology and Mechanism of Action Alpha2 ...
Veterinary Pharmacology and Therapeutics
Veterinary Pharmacology and Therapeutics
Jim E. Riviere, Mark G. Papich, 2009
Xylazine HYDROCHLORIDE Synonyms: Prestwick_962, Spectrum_001267, Xylazi- num, Xilazina, Bay 1470, WH 7286; ... Xylazine was the first OC2- adrenergic agonist used in veterinary medicine and its clinical use was first described in ...
Development of Google searches

Blog posts on the term
The Xylazine Zombie Threat | Who is Patient Zero?
Your source for all of the latest news on the impending zombie apocalypse. (by SoCal Chica)
Acta Veterinaria Scandinavica | Full text | Physiological evaluation of free-ranging moose (Alces alces) immobilized with etorphine-xylazine-acepromazine in Northern Sweden
Evaluation of physiology during capture and anesthesia of free-ranging wildlife is useful for determining the effect that capture methods have on both ecological research results and animal welfare. This study evaluates capture and anesthesia of moose (Alces alces) with etorphine-Xylazine-acepromazine in Northern Sweden.
PreventingOverdose.ca » Xylazine a New Potentially Fatal Addition to Other Drugs of Abuse
Posted on April 16, 2013 by admin.
SATPP | Full text | Xylazine (veterinary sedative) use in Puerto Rico
Human Xylazine use in Puerto Rico merits particular attention for its unprecedented scale and depth. Although Puerto Rican injecting drug users (IDUs) have reported using this drug since the early 2000s, little is being done in the research and service delivery sectors as it is claimed that Xylazine severely impacts the health of its users. This report provides information on Xylazine use and its associated harms. Data from one semi-structured interview collected in New York City (2007-2008) as part of a larger research study with migrant Puerto Rican drug users is presented as a case study. Xylazine, a veterinary sedative, is an adulterant and complement to other drugs and its chronic use is reported to be associated with physical deterioration. Because human Xylazine use has been reported in other locations outside of Puerto Rico, this substance could also emerge as an adulterant in other markets to the levels currently experienced in Puerto Rico. Research and interventions are needed to provide adequate services on the island, better understand how the use of Xylazine affects its users, and to reduce the possibility of increased Xylazine use on the state-side.
Xylazine, Verteporfin, Methyl 4-hydroxy-3-methoxycinnamate New Xylazine Is Double The Enjoyable | margin3pea
This WordPress.com site is the bee's knees
Buy Xylazine HCl | Adrenergic Receptor Antagonists & Agonists | Price | IC50 | Research only
Xylazine HCl is α2 class of adrenergic receptor agonist.…Quality confirmed by NMR & HPLC. See customer reviews, validations & product citations
'Xylazine, Verteporfin, Methyl 4-hydroxy-3-methoxycinnamate T', adelbertwade's blog message on Netlog
Netlog is a community where users can keep in touch with and extend their social network. On Netlog, you can create your own web page with a blog, upload pictures, watch videos, find events and play games.
Rats were implanted under ketamine xylazine anesthesia mg | Online Peptide Guide
Posted on May 2, 2013 by admin.
Xylazine Sedation Antagonized With Tolazoline
Vol. 21, No. 1 January 1999V20TH ANNIVERSARYCERefereed Peer ReviewFOCAL POINT 5Because of their actions onspecific receptors, the clinical actions of α2-adrenoceptor agonists can be antagonized by selective antagonists.
Account Suspended